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Product Name
Human Cathepsin D/CTSD (His Tag) recombinant protein
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Description
Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
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Protein name
Cathepsin D
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Protein short names
CD; CATD; CTSD; CLN10; CATHEPSIN D; MGC2311; CPSD; HEL-S-130P
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Uniprot ID
P07339
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Gene Name
CTSD; CPSD
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the pro form of human CTSD (P07339) (Met 1-Leu 412) was fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The secreted recombinant human CTSD (pro form) consists of 405 amino acids and has a predicted molecular mass of 44 kDa. As a result of different glycosylation, the apparent molecular mass of rhCTSD is approximately 40-110 kDa in SDS-PAGE under reducing conditions.
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Purity
> 97 % as determined by SDS-PAGE
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Activity
Measured by its ability to bind biotinylated human CTSS-His (Cat:501120) in a functional ELISA.
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Validations
Human Cathepsin D / CTSD Protein (His Tag) SDS-PAGE
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