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Product Name
Caspase 2/p18 antibody
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Description
Caspase 2/p18 Rabbit Polyclonal antibody. Positive WB detected in HEK-293 cells, Jurkat cells, mouse kidney tissue. Positive IF detected in HEK-293 cells. Observed molecular weight by Western-blot: 45 kDa,32 kDa
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Tested applications
ELISA, WB, IF
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
CASP 2 antibody; CASP2 antibody; Caspase 2 antibody; Caspase 2/p18 antibody; Caspase2 antibody; ICH 1L antibody; ICH 1L/1S antibody; ICH1 antibody; NEDD 2 antibody; NEDD2 antibody; Protease ICH 1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Caspase 2/p18 recombinant protein (Accession Number: NM_032982). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IF: 1:20-1:200
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Validations
HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:108874(Caspase 2 Antibody) at dilution of 1:600
Immunofluorescent analysis of (-20oc Ethanol) fixed HEK-293 cells using Catalog No:108874(Caspase 2 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Background
CASP2(Caspase-2) is also named as ICH1, NEDD2 and belongs to the peptidase C14A family.It is involved in the activation cascade of caspases responsible for apoptosis execution and might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.It has 2 isoforms produced by alternative splicing and can exists almost as a dimer in solution(PMID:15865942).
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