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Human Cardiotrophin 1 / CTF1 / CT 1 (Fc Tag) recombinant protein

Cat.#: 500566

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Product Information

  • Product Name
    Human Cardiotrophin 1 / CTF1 / CT 1 (Fc Tag) recombinant protein
  • Documents
  • Description
    Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.
  • Protein name
    Cardiotrophin-1
  • Protein short names
    CT-1; CARDIOPHIN 1; CARDIOTROPHIN 1; CT1; CTF1
  • Uniprot ID
    Q16619
  • Gene Name
    CTF1
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human CTF1(NP_001321.1)(Ser2-Ala201) was expressed with the fused Fc region of human IgG1 at the N-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human CTF1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 460 amino acids and has a predicted molecular mass of 49.5 kDa. The apparent molecular mass of the protein is approximately 54 and 37 kDa in SDS-PAGE under reducing conditions due to glycosylation.
  • Purity
    (76.0+8.5) % as determined by SDS-PAGE
  • Activity
    Measured in a cell proliferation assay using TF-1 human erythroleukemic cells.
    The ED50 for this effect is typically 0.015-0.06 μg/mL.
  • Validations

    Human Cardiotrophin-1 / CTF1 Protein (Fc Tag) SDS-PAGE

    Human Cardiotrophin-1 / CTF1 Protein (Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"