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Product Name
Carboxypeptidase A6 antibody
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Description
Carboxypeptidase A6 Rabbit Polyclonal antibody. Positive IF detected in HepG2 cells. Positive IHC detected in human gliomas tissue. Positive WB detected in HepG2 cells, mouse brain tissue. Observed molecular weight by Western-blot: 65 kDa or 51 kDa
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Tested applications
ELISA, WB, IHC, IF
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
Carboxypeptidase A6 antibody; Carboxypeptidase B antibody; CPA6 antibody; CPAH antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Carboxypeptidase A6 recombinant protein (Accession Number: NM_020361). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
IF: 1:10-1:100
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Validations
HepG2 cells were subjected to SDS PAGE followed by western blot with Catalog No:108851(CPA6 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human gliomas using Catalog No:108851(CPA6 antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human gliomas using Catalog No:108851(CPA6 antibody) at dilution of 1:100 (under 40x lens)
Immunofluorescent analysis of HepG2 cells using Catalog No:108851(CPA6 Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Background
Carboxypeptidase A6 is an extracellular matrixbound metallocarboxypeptidase (CP) that has been implicated in Duane syndrome, a neurodevelopmental disorder in which the lateral rectus extraocularmuscle is not properly innervated.Consistent with a role inDuane syndrome, CPA6 is expressed in a number of chondrocytic and nervous tissues during embryogenesis.It has three isoforms.The product recognizes the C-terminal of this protein.
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