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Product Name
Carboxypeptidase A1 antibody
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Description
Carboxypeptidase A1 Rabbit Polyclonal antibody. Positive WB detected in mouse pancreas tissue. Positive IHC detected in human placenta tissue, human kidney tissue, human liver tissue, human lung tissue, human spleen tissue. Observed molecular weight by Western-blot: 47 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
Carboxypeptidase A1 antibody; CPA antibody; CPA1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Carboxypeptidase A1 recombinant protein (Accession Number: NM_001868). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
mouse pancreas tissue were subjected to SDS PAGE followed by western blot with Catalog No:108847(CPA1 antibody) at dilution of 1:3000
Immunohistochemical of paraffin-embedded human placenta using Catalog No:108847(CPA1 antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human placenta using Catalog No:108847(CPA1 antibody) at dilution of 1:100 (under 40x lens)
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Background
CPA1(Carboxypeptidase A1) is also named as CPA and belongs to the the peptidase M14 family. CPA1 is one of the genes whose expression in the pancreas and the protein which it encodes is synthesized as an inactive precursor, procPA1, which is processed to the active enzyme by the proteolytic removal of the 95-amino acid N-terminal prodomain. The mature CPA1 is not secreted and is trapped and degraded intracellularly(PMID:8639628). This antibody is speicific to CPA1.
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