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Product Name
Human CMBL (His Tag) recombinant protein
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Description
Cysteine hydrolase. Can convert the prodrug olmesartan medoxomil into its pharmacologically active metabolite olmerstatan, an angiotensin receptor blocker, in liver and intestine. May also activate beta-lactam antibiotics faropenem medoxomil and lenampicillin.
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Protein name
Carboxymethylenebutenolidase homolog
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Protein short names
JS-1; 2310016A09RIK; FLJ23617
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Uniprot ID
Q96DG6
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Gene Name
CMBL
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human CMBL (Q96DG6) (Met 1-Met 245) was expressed, with a N-terminal polyhistidine tag.
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Protein Species
Human
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Molecular weight
The recombinant human CMBL comprises 260 amino acids and has a calculated molecular mass of 30 kDa. It migrates as an approximately 28 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 97 % as determined by SDS-PAGE
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Validations
Human CMBL Protein (His Tag) SDS-PAGE
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