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Product Name
CAPRIN1 Polyclonal Antibody
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Description
Polyclonal antibody to CAPRIN1
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Tested applications
WB, IHC
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Species reactivity
Human, Mouse, Rat
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Alternative names
CAPRIN1 antibody; GPIAP1 antibody; GPIP137 antibody; GRIP137 antibody; M11S1 antibody; RNG105 antibody; p137GPI antibody; caprin-1 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant protein of human CAPRIN1
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
IHC 1:100 - 1:200 -
Validations
Western blot - CAPRIN1 Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using CAPRIN1 antibody at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 90s.
Immunohistochemistry - CAPRIN1 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded mouse brain using CAPRIN1 antibody (40x lens).
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Background
May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"