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Cannabinoid receptor 1 antibody

Cat.#: 108930

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Special Price 239.0 USD

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Product Information

  • Product Name
    Cannabinoid receptor 1 antibody
  • Documents
  • Description
    Cannabinoid receptor 1 Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue, mouse testis tissue, SH-SY5Y cells. Positive IHC detected in mouse brain tissue. Positive FC detected in SH-SY5Y cells. Observed molecular weight by Western-blot: 53 kDa
  • Tested applications
    ELISA, WB, IHC, FC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    CANN6 antibody; Cannabinoid receptor 1 antibody; cannabinoid receptor 1 (brain) antibody; CB R antibody; CB1 antibody; CB1A antibody; CB1K5 antibody; CB1R antibody; CNR antibody; CNR1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Cannabinoid receptor 1 recombinant protein (Accession Number: NM_001160259). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:50-1:500

  • Validations

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:108930(CNR1 Antibody) at dilution of 1:1000

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:108930(CNR1 Antibody) at dilution of 1:1000

    Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:108930(CNR1 Antibody) at dilution of 1:100 (under 10x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

    Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:108930(CNR1 Antibody) at dilution of 1:100 (under 10x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

    Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:108930(CNR1 Antibody) at dilution of 1:100 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

    Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:108930(CNR1 Antibody) at dilution of 1:100 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

    1X10^6 SH-SY5Y cells were stained with 0.2ug CNR1 antibody (Catalog No:108930, red) and control antibody (blue). Fixed with 4% PFA blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1500.

    1X10^6 SH-SY5Y cells were stained with 0.2ug CNR1 antibody (Catalog No:108930, red) and control antibody (blue). Fixed with 4% PFA blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1500.

  • Background
    Cannabinoid receptor 1 (CNR1, or CB1) and CNR2 (CB2) are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family. The CB1 receptor is expressed mainly in the brain. The CB2 receptor is expressed mainly in the immune system and in hematopoietic cells. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana.
  • References
    • Kaminitz A, Barzilay R, Segal H. Dominant negative DISC1 mutant mice display specific social behaviour deficits and aberration in BDNF and cannabinoid receptor expression. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. 15(1):76-82. 2014.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"