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Product Name
CaMKII beta antibody
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Description
CaMKII beta Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue. Positive IF detected in HEK-293 cells. Positive IHC detected in human skeletal muscle tissue, human brain tissue. Observed molecular weight by Western-blot: 55-60 kDa
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Tested applications
ELISA, WB, IHC, IF
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
CaM kinase II subunit beta antibody; CAM2 antibody; CaMK II subunit beta antibody; CAMK2 antibody; CAMK2B antibody; CAMKB antibody; CaMKII beta antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_001220). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
IF: 1:20-1:200
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Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:108917(CAMK2B antibody) at dilution of 1:1000
Immunohistochemical of paraffin-embedded human skeletal muscle using Catalog No:108917(CAMK2B antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human skeletal muscle using Catalog No:108917(CAMK2B antibody) at dilution of 1:50 (under 40x lens)
Immunofluorescent analysis of HEK-293 cells using Catalog No:108917(CAMK2B Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Background
CaMKII beta, also named as CAM2 and CAMKB, belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and CaMK subfamily. CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. CAMK2B is a member of the NMDAR signaling complex in excitatory synapses, it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity. This antibody can recognized all the isoform except 7 of CaMKII beta.
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