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Product Name
Cadherin-16 antibody
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Description
Cadherin-16 Rabbit Polyclonal antibody. Positive WB detected in human kidney tissue, HEK-293 cells, mouse kidney tissue. Positive IHC detected in human kidney tissue. Observed molecular weight by Western-blot: 130 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
cadherin 16 antibody; KSP cadherin antibody; Cadherin-16 antibody; CDH16 antibody; Kidney specific cadherin antibody; Ksp cadherin antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Cadherin-16 recombinant protein (Accession Number: NM_004062). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:50-1:500
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Validations
human kidney tissue were subjected to SDS PAGE followed by western blot with Catalog No:108773(CDH16 antibody) at dilution of 1:400
Immunohistochemistry of paraffin-embedded human kidney tissue slide using Catalog No:108773(CDH16 Antibody) at dilution of 1:200 (under 10x lens).
Immunohistochemistry of paraffin-embedded human kidney tissue slide using Catalog No:108773(CDH16 Antibody) at dilution of 1:200 (under 40x lens).
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Background
Cadherin-16 (CDH16), also known as kidney-specific cadherin (Ksp-cadherin), is a tissue-specific member of the cadherin family of adhesion molecules (PMID: 7615566). It is a glycoprotein expressed by tubular epithelial cells in the kidney. Cadherin-16 expression is down-regulated in renal cell carcinoma, suggesting a role in tumor suppression (PMID: 15886705).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"