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Product Name
Human KSP-Cadherin/Cadherin-16 (His Tag) recombinant protein
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Description
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
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Protein name
Cadherin-16
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Protein short names
UNQ695/PRO1340; CADHERIN-16; KIDNEY-SPECIFIC CADHERIN; KSP-CADHERIN; CDH16
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Uniprot ID
O75309
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Gene Name
CDH16; UNQ695/PRO1340
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the extracellular domain of human CDH16 (NP_004053.1) (Met 1-Ala 786) was expressed, fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human CDH16 comprises 779 amino acids and has a calculated molecular mass of 84.8 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 100 kDa protein in SDS-PAGE under reducing conditions.
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Purity
> 70 % as determined by SDS-PAGE
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Activity
Measured by the ability of the immobilized protein to support the adhesion of MCF-7 human breast adenocarcinoma cells.
When cells are added to CDH16-His coated plates (10 μg/mL, 100 μL/well), approximately 20-40% will adhere specifically after 60 minutes at 37 ℃. -
Validations
Human KSP-Cadherin / Cadherin-16 / CDH16 Protein (His Tag) SDS-PAGE
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