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Product Name
CA11 antibody
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Description
CA11 Rabbit Polyclonal antibody. Positive IHC detected in human brain tissue, human lung tissue, human ovary tissue, human placenta tissue, human spleen tissue, human testis tissue. Positive WB detected in human kidney tissue. Observed molecular weight by Western-blot: 36 kda, 45 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
CA RP II antibody; CA RP XI antibody; CA XI antibody; CA11 antibody; carbonic anhydrase XI antibody; CARP 2 antibody; CARP XI antibody; CARP2 antibody; CARPX1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CA11 recombinant protein (Accession Number: NM_001217). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
human kidney tissue were subjected to SDS PAGE followed by western blot with Catalog No:108743(CA11 antibody) at dilution of 1:400
Immunohistochemical of paraffin-embedded human brain using Catalog No:108743(CA11 antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human brain using Catalog No:108743(CA11 antibody) at dilution of 1:50 (under 40x lens)
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Background
CA11(Carbonic anhydrase-related protein 11) is also named as CARP2, CARP XI and belongs to the alpha-carbonic anhydrase family. CARP XI is observed in the cerebellum, cerebrum, liver, stomach, small intestine, colon, kidney, and testis by immunohistochemical and in the cerebellum, the most prominent signal is located in the Purkinje cells(PMID:20356370). CARP XI contains a hydrophobic N-terminal region for a possible signal sequence and asparagine glycosylation site and it plays a general role in the human central nervous system(PMID: 10350627).
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