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Product Name
C8A antibody
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Description
C8A Rabbit Polyclonal antibody. Positive WB detected in Transfected HEK-293 cells.
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
C8A antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of C8A recombinant protein (Accession Number: NM_000562). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:108793(C8A Antibody) at dilution of 1:700
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Background
C8 is a component of the complement system and contains three polypeptides, alpha, beta and gamma. Complement component C8 alpha chain (C8A) is a constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C8A inserts into the target membrane, but does not form pores by itself. Mutations in the C8A gene cause complement C8 alpha-gamma deficiency.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"