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Product Name
C4orf49 antibody
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Description
C4orf49 Rabbit Polyclonal antibody. Positive IHC detected in human ovary tissue, human testis tissue. Positive WB detected in SKOV-3 cells, A2780 cells. Observed molecular weight by Western-blot: 33-36 kDa
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human; other species not tested.
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Alternative names
C4orf49 antibody; CESP-1 antibody; Corneal endothelium-specific protein 1 antibody; HUMMR antibody; MGARP antibody; OSAP antibody; Ovary specific acidic protein antibody; Protein MGARP antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of C4orf49 recombinant protein (Accession Number: NM_032623). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
SKOV-3 cells were subjected to SDS PAGE followed by western blot with Catalog No:108732(C4orf49 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human testis slide using Catalog No:108732(C4orf49 Antibody) at dilution of 1:50
Immunohistochemistry of paraffin-embedded human ovary slide using Catalog No:108732(C4orf49 Antibody) at dilution of 1:50
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Background
The protein MGARP, also named as C4ORF49, CESP1, HUMMR, OSAP and GS3582, plays a role in the trafficking of mitochondria along microtubules. It regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hypoxia. MGARP is localized to the mitochondria in cultured human CE, and its N-terminal seems to be processed after mitochondrial import. The MW of MGARP is about 33-36 kDa(PMID: 16565373).
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