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Product Name
C1S antibody
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Description
C1S Rabbit Polyclonal antibody. Positive IHC detected in human liver cancer tissue. Positive WB detected in human blood tissue, COLO 320 cells. Observed molecular weight by Western-blot: 88 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
C1 esterase antibody; C1S antibody; Complement C1s subcomponent antibody; FLJ44757 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of C1S recombinant protein (Accession Number: XM_005253760). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:1000-1:10000
IHC: 1:20-1:200
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Validations
human blood tissue were subjected to SDS PAGE followed by western blot with Catalog No:108690(C1S antibody) at dilution of 1:2000
Immunohistochemical of paraffin-embedded human liver cancer using Catalog No:108690(C1S antibody) at dilution of 1:50 (under 40x lens)
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Background
The first component of complement is a calcium-dependent complex of the 3 subcomponents C1q, C1r, and C1s. The serine protease subunits C1r and C1s form a Ca(2+)-dependent C1s-C1r-C1r-C1s tetramer. C1r activates C1s so that it can, in turn, activate C2 and C4. C1s is a glycoprotein of approximately 88 kDa, which is activated by cleavage into an A chain and a B chain.
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