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Product Name
C1QC Polyclonal Antibody
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Description
Polyclonal antibody to C1QC
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Tested applications
WB, IHC
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Species reactivity
Human
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Alternative names
C1QC antibody; C1Q-C antibody; C1QG antibody; complement C1q C chain antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human C1QC (NP_001107573.1).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
IHC 1:50 - 1:100 -
Validations
Western blot - C1QC Polyclonal Antibody
Western blot analysis of extracts of human serum, using C1QC antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 5s.
Immunohistochemistry - C1QC Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human lung using C1QC antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - C1QC Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human liver using C1QC antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - C1QC Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human colon using C1QC antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - C1QC Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human stomach using C1QC antibody at dilution of 1:100 (40x lens).
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Background
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"