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Product Name
C11orf30 Polyclonal Antibody
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Description
Polyclonal antibody to C11orf30
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Tested applications
WB, IF
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Species reactivity
Human, Mouse
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Alternative names
EMSY antibody; C11orf30 antibody; GL002 antibody; BRCA2-interacting transcriptional repressor EMSY antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1153-1322 of human C11orf30 (NP_064578.2).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
IF 1:50 - 1:100 -
Validations
Western blot - C11orf30 Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using C11orf30 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 90s.
Immunofluorescence - C11orf30 Polyclonal Antibody
Immunofluorescence analysis of U2OS cells using C11orf30 antibody .
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Background
Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2. As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"