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Product Name
C10orf67 antibody
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Description
C10orf67 Rabbit Polyclonal antibody. Positive WB detected in PC-3 cells, A549 cells, human testis tissue. Observed molecular weight by Western-blot: 18-21 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
C10orf67 antibody; RP11 792P23.2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of C10orf67 recombinant protein (Accession Number: NM_153714). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
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Validations
PC-3 cells were subjected to SDS PAGE followed by western blot with Catalog No:108634(C10orf67 Antibody) at dilution of 1:300
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Background
RNF17 also termed as ring finger protein 17 is a 1623 amino acid protein, which contains 1 ring type zinc finger and 4 tudor domains. RNF17 is specifically expressed in testis. The RING finger motif presents in many ubiquitin E3 ligases. RNF17 interacts with all four members of the Mad family (Mad1, Mxi1, Mad3 and Mad4), which are basic-helix-loop-helix-leucine zipper transcription factors of the Myc oncoprotein network. RNF17 is component of the tectonic-like complex, which is required for ciliogenesis and sonic hedgehog/SHH signaling. RNF17 is able to form dimers or polymers both in vitro and in vivo, indicating that it may play a role in the assembly of RNF17 granules. RNF17 encodes a novel key regulator of spermiogenesis.
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