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Product Name
Human I-TAC / CXCL11 recombinant protein
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Description
Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.
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Protein name
C-X-C motif chemokine 11
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Protein short names
H174; IP9; MEMBER 9B; BETA-R1; CHEMOKINE (C-X-C MOTIF) LIGAND 11; CXCL11; ITAC; SCYB9B; SMALL INDUCIBLE CYTOKINE B11; B-R1; SMALL-INDUCIBLE CYTOKINE B11; MEMBER 11; I-TAC; CXC11; SMALL INDUCIBLE CYTOKINE SUBFAMILY B (CYS-X-CYS); IP-9; SCYB11; C-X-C MOTIF CHEMOKINE 11; INTERFERON GAMMA-INDUCIBLE PROTEIN 9; INTERFERON-INDUCIBLE T-CELL ALPHA CHEMOATTRACTANT; BETAR1
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Uniprot ID
O14625
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Gene Name
CXCL11; ITAC; SCYB11; SCYB9B
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the mature form of human CXCL11 (O14625) (Phe22-Phe94) was expressed with an initial Met.
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Protein Species
Human
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Molecular weight
The recombinant human CXCL11 consists of 73 amino acids and predicts a molecular mass of 8.3 KDa. It migrates as an approximately 9 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human I-TAC / CXCL11 Protein SDS-PAGE
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