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Product Name
Human CCL13/MCP-4 (His Tag) recombinant protein
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Description
Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens.
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Protein name
C-C motif chemokine 13
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Protein short names
MCP-4
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Uniprot ID
Q99616
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Gene Name
CCL13; MCP4; NCC1; SCYA13
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Source/Expression Host
Yeast
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Expression Plasmid/cDNA
A DNA sequence encoding human CCL13 (NP_005399.1) (Gln24-Thr98) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human CCL13 consists of 85 amino acids and predicts a molecular mass of 10 KDa. It migrates as an approximately 14 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human CCL13 / MCP-4 Protein (His Tag) SDS-PAGE
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