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Product Name
BSAP,PAX5 antibody
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Description
BSAP,PAX5 Mouse Monoclonal antibody. Positive WB detected in Ramos cells, Daudi cells, Raji cells. Observed molecular weight by Western-blot: 42 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
BSAP antibody; BSAP antibody; PAX5 antibody; paired box 5 antibody; Paired box protein Pax 5 antibody; PAX5 antibody
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Isotype
Mouse IgG1
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Preparation
This antibody was obtained by immunization of BSAP,PAX5 recombinant protein (Accession Number: NM_016734). Purification method: Protein G purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
Ramos cells were subjected to SDS PAGE followed by western blot with Catalog No:107025(BSAP,PAX5 Antibody) at dilution of 1:1500
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Background
PAX5, also named B-cell specific activator protein (BSAP), is a member of the highly conserved paired box (PAX)-domain family of transcription factors. PAX5 is essential in normal B-cell lymphopoiesis. It is expressed in pro-B, pre-B and mature B lymphocytes but not in plasma cells. PAX5 is a common target in leukemogenesis of B-ALL ( B-lineage acute lymphoblastic leukemia) along with CDKN2A. Owing to its frequent deletion in B-ALL, PAX5 could be used as one of the molecular markers in diagnosis and monitoring of the disease. This antibody is specific to PAX5. It will not cross react with other PAX members.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"