BRN2-Specific antibody

Cat.#: 108595

Size:

Special Price 239.0 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    BRN2-Specific antibody
  • Documents
  • Description
    BRN2-Specific Rabbit Polyclonal antibody. Positive WB detected in HeLa cells, A375 cells, HEK-293 cells. Positive IHC detected in human brain tissue. Observed molecular weight by Western-blot: 47kd
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    Brain 2 antibody; Brn 2 antibody; BRN2 antibody; OCt 7 antibody; OCT7 antibody; OCtamer binding protein 7 antibody; OTF 7 antibody; OTF7 antibody; POU class 3 homeobox 2 antibody; POU3F2 antibody; POUF3 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Peptide (Accession Number: NM_005604). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:117242(POU3F2-Specific antibody) at dilution of 1:600

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:117242(POU3F2-Specific antibody) at dilution of 1:600

    Immunohistochemical of paraffin-embedded human brain using Catalog No:117242(POU3F2-Specific antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human brain using Catalog No:117242(POU3F2-Specific antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human brain using Catalog No:117242(POU3F2-Specific antibody) at dilution of 1:100 (under 40x lens)

    Immunohistochemical of paraffin-embedded human brain using Catalog No:117242(POU3F2-Specific antibody) at dilution of 1:100 (under 40x lens)

  • Background
    POU3F2 belongs to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. It shares a highly homologous region that referred to as the POU domain. POU3F2 is a Class III POU genes that expressed predominantly in the central nervous system (CNS). It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression. POU3F2 is required for maintaining neural cell differetiation and has a role in the production and positioning of neocortical neurons.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"