BRN2 antibody

Cat.#: 108594

Size:

Special Price 239.0 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    BRN2 antibody
  • Documents
  • Description
    BRN2 Rabbit Polyclonal antibody. Positive IHC detected in human gliomas tissue, human ovary tissue, human placenta tissue, human skin tissue, human spleen tissue. Positive WB detected in Jurkat cells. Observed molecular weight by Western-blot: 47kd
  • Tested applications
    ELISA, IHC, WB
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    Brain 2 antibody; Brn 2 antibody; BRN2 antibody; OCt 7 antibody; OCT7 antibody; OCtamer binding protein 7 antibody; OTF 7 antibody; OTF7 antibody; POU class 3 homeobox 2 antibody; POU3F2 antibody; POUF3 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of BRN2 recombinant protein (Accession Number: NM_005604). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:117241(POU3F2 antibody) at dilution of 1:1200

    Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:117241(POU3F2 antibody) at dilution of 1:1200

    Immunohistochemical of paraffin-embedded human gliomas using Catalog No:117241(POU3F2 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human gliomas using Catalog No:117241(POU3F2 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human gliomas using Catalog No:117241(POU3F2 antibody) at dilution of 1:100 (under 40x lens)

    Immunohistochemical of paraffin-embedded human gliomas using Catalog No:117241(POU3F2 antibody) at dilution of 1:100 (under 40x lens)

  • Background
    POU3F2 belongs to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. It shares a highly homologous region that referred to as the POU domain. POU3F2 is a Class III POU genes that expressed predominantly in the central nervous system (CNS). It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression. POU3F2 is required for maintaining neural cell differetiation and has a role in the production and positioning of neocortical neurons.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"