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Product Name
BMP3 antibody
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Description
BMP3 Rabbit Polyclonal antibody. Positive IHC detected in human liver cancer tissue, human liver tissue, human lung cancer tissue. Positive WB detected in Recombinant protein.
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human; other species not tested.
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Alternative names
BMP 3 antibody; BMP 3A antibody; BMP3 antibody; BMP3A antibody; bone morphogenetic protein 3 antibody; Bone morphogenetic protein 3A antibody; Osteogenin antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of BMP3 recombinant protein (Accession Number: NM_001201). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
Recombinant protein were subjected to SDS PAGE followed by western blot with Catalog No:117197(BMP3 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using Catalog No:117197(BMP3 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using Catalog No:117197(BMP3 Antibody) at dilution of 1:50 (under 40x lens)
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Background
BMP3 belongs to the transforming growth factor-beta (TGFB) superfamily. BMP3 plays an important role in embryonic development by inducing and patterning early skeletal formation. BMP3 has also been reported as a negative growth regulator in bone marrow progenitor cells through the inhibition of DNA synthesis and proliferation. Additionally, recent studies have revealed that BMP3 contributes to tumor development and progression.
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References
- Wei Y, Wu Y, Zeng B, Zhang H. Effects of sodium fluoride treatment in vitro on cell proliferation, BMP-2 and BMP-3 expression in human osteosarcoma MG-63 cells. Biological trace element research. 162(1-3):18-25. 2014.
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