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Product Name
BLOC1S3 Polyclonal Antibody
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Description
Polyclonal antibody to BLOC1S3
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Tested applications
IHC, IF
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Species reactivity
Human, Mouse, Rat
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Alternative names
BLOC1S3 antibody; BLOS3 antibody; HPS8 antibody; RP antibody; biogenesis of lysosomal organelles complex 1 subunit 3 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-202 of human BLOC1S3 (NP_997715.1).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
IHC 1:50 - 1:200
IF 1:50 - 1:200 -
Validations
Immunohistochemistry - BLOC1S3 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human colon using BLOC1S3 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - BLOC1S3 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human colon carcinoma using BLOC1S3 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - BLOC1S3 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human breast cancer using BLOC1S3 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - BLOC1S3 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human uterine cancer using BLOC1S3 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - BLOC1S3 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded mouse testis using BLOC1S3 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - BLOC1S3 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded mouse kidney using BLOC1S3 antibody at dilution of 1:100 (40x lens).
Immunofluorescence - BLOC1S3 Polyclonal Antibody
Immunofluorescence analysis of NIH-3T3 cells using BLOC1S3 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence - BLOC1S3 Polyclonal Antibody
Immunofluorescence analysis of U-2 OS cells using BLOC1S3 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence - BLOC1S3 Polyclonal Antibody
Immunofluorescence analysis of C6 cells using BLOC1S3 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence - BLOC1S3 Polyclonal Antibody
Immunofluorescence analysis of NIH-3T3 cells using BLOC1S3 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence - BLOC1S3 Polyclonal Antibody
Immunofluorescence analysis of U-2 OS cells using BLOC1S3 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
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Background
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"