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Product Name
Betacellulin antibody
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Description
Betacellulin Rabbit Polyclonal antibody. Positive WB detected in Transfected HEK-293 cells. Positive IHC detected in human small intestine tissue, human breast cancer tissue.
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human; other species not tested.
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Alternative names
betacellulin antibody; BTC antibody; Probetacellulin antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Betacellulin recombinant protein (Accession Number: XM_011532211). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:117133(BTC Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human small intestine tissue slide using Catalog No:117133(BTC Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human small intestine tissue slide using Catalog No:117133(BTC Antibody) at dilution of 1:50 (under 40x lens)
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Background
Betacellulin (BTC), a member of the epidermal growth factor (EGF) family, binds and activates ErbB1 and ErbB4 homodimers. BTC is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor. BTC was expressed in tumors and involved in tumor growth progression.
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References
- Kwon S, Kim MS, Lee ES, Sohn JS, Park JK. A quantum dot-based microfluidic multi-window platform for quantifying the biomarkers of breast cancer cells. Integrative biology : quantitative biosciences from nano to macro. 6(4):430-7. 2014.
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