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Human HEXA (Subunit A, His Tag) recombinant protein

Cat.#: 501556

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Product Information

  • Product Name
    Human HEXA (Subunit A, His Tag) recombinant protein
  • Documents
  • Description
    Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. The form B is active against certain oligosaccharides. The form S has no measurable activity.
  • Protein name
    Beta-hexosaminidase subunit alpha
  • Protein short names
    HEX-1; TSD; HEXA; HEXOSAMINIDASE A; MGC99608
  • Uniprot ID
    P06865
  • Gene Name
    HEXA
  • Source/Expression Host
    Baculovirus-Insect Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human HEXA (AAD13932.1) (Met 1-Thr 529) was fused with a polyhistidine tag at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human HEXA consists of 517 amino acids and predicts a molecular mass of 59.7 kDa. It migrates as an approximately 64 kDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Activity
    Measured by its ability to hydrolyze 4-methylumbelliferyl-N-acetyl-β-D-glucosaminide (4-MU-Glc-NAc).
    The specific activity is >1,250 pmoles/min/μg.
  • Validations

    Human Hexosaminidase A / HEXA Protein (Subunit A, His Tag) SDS-PAGE

    Human Hexosaminidase A / HEXA Protein (Subunit A, His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"