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Product Name
BCRP/ABCG2 antibody
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Description
BCRP/ABCG2 Mouse Monoclonal antibody. Positive WB detected in Jurkat cells. Positive IP detected in NCCIT cell. Observed molecular weight by Western-blot: 70-80; 140-160 kDa
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Tested applications
ELISA, IP, WB
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Species reactivity
Human; other species not tested.
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Alternative names
ABC15 antibody; ABCG2 antibody; ABCP antibody; BCRP/ABCG2 antibody; BMDP antibody; CD338 antibody; MRX antibody; MXR antibody; MXR1 antibody
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Isotype
Mouse IgG1
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Preparation
This antibody was obtained by immunization of BCRP/ABCG2 recombinant protein (Accession Number: NM_004827). Purification method: Caprylic acid/ammonium sulfate precipitation.
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Clonality
Monoclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:500-1:5000
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Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:107082(BCRP,ABCG2 antibody) at dilution of 1:500
IP Result of anti-BCRP,ABCG2 (IP:Catalog No:107082, 4ug; Detection:Catalog No:107082 1:1000) with NCCIT cell lysate 2000ug.
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Background
BCRP (breast cancer resistance protein) confers a broad spectrum of drug resistance and the expression of BCRP is enhanced in several cancer cell models. It has ATPase activity and belongs to a family of multiple drug resistant proteins. Data also indicated that BCRP might be an early marker for some stem cells.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"