-
Product Name
BAP1 antibody
- Documents
-
Description
BAP1 Rabbit Polyclonal antibody. Positive WB detected in A2780 cells, human placenta tissue, mouse ovary tissue. Observed molecular weight by Western-blot: 91 kDa
-
Tested applications
ELISA, WB
-
Species reactivity
Human, Mouse; other species not tested.
-
Alternative names
BAP1 antibody; BRCA1 assOCiated protein 1 antibody; Cerebral protein 6 antibody; DKFZp686N04275 antibody; FLJ35406 antibody; FLJ37180 antibody; HUCEP 13 antibody; hucep 6 antibody; KIAA0272 antibody; UCHL2 antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of BAP1 recombinant protein (Accession Number: NM_004656). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:200-1:2000
-
Validations
A2780 cells were subjected to SDS PAGE followed by western blot with Catalog No:108419(BAP1 antibody) at dilution of 1:300
-
Background
BRCA1-associated protein-1 (BAP1),also named as KIAA0272, hucep-6, DKFZp686N04275, FLJ35406, FLJ37180, HUCEP-13, is a deubiquitinating enzyme whose function in the control of the cell cycle requires both its deubiquitinating activity and nuclear localization(PMID:22374320). It helps to control cell proliferation by regulating HCFC1 protein levels and by associating with genes involved in the G(1)-S transition)(PMID:19188440). Defects in BAP1 may be a cause of mesothelioma malignant (MESOM)(PMID:21642991) and tumor predisposition syndrome (TPDS)(PMID:21874003). The all BAP1s except those of C. quinquefasciatus have a molecular mass of more than 90 kDa(PMID:22374320).
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"