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Product Name
B3GNT5 Polyclonal Antibody
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Description
Polyclonal antibody to B3GNT5
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Tested applications
WB
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Species reactivity
Human, Mouse, Rat
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Alternative names
B3GNT5 antibody; B3GN-T5 antibody; beta3Gn-T5 antibody; lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human B3GNT5
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, pH7.3.
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Storage instructions
Store at 4℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
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Validations
Western blot - B3GNT5 Polyclonal Antibody
Western blot analysis of extracts of mouse lung, using B3GNT5 antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
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Background
Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc(4)Cer; paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide (nLc(5)Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"