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Product Name
B2M antibody
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Description
B2M Mouse Monoclonal antibody. Positive IHC detected in human prostate cancer tissue, human renal cell carcinoma tissue. Positive WB detected in Raji cells. Observed molecular weight by Western-blot: 13 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human; other species not tested.
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Alternative names
B2M antibody; beta 2 microglobulin antibody; HDCMA22P antibody
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Isotype
Mouse IgG2b
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_004048). Purification method: Protein A purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:1000-1:10000
IHC: 1:20-1:200
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Validations
Raji cells were subjected to SDS PAGE followed by western blot with Catalog No:107076(B2M Antibody) at dilution of 1:4000
Immunohistochemistry of paraffin-embedded human prostate cancer tissue slide using Catalog No:107076 (B2M Antibody) at dilution of 1:200 (under 10x lens)
Immunohistochemistry of paraffin-embedded human prostate cancer tissue slide using Catalog No:107076 (B2M Antibody) at dilution of 1:200 (under 40x lens)
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Background
Beta-2-microglobulin (B2M) is a component of MHC class I molecules, which are present on the surface of nearly all nucleated cells. It can be found in body fluids under physiologic conditions as a result of shedding from cell surfaces or intracellular release. B2M has various biological functions, including antigen presentation. Investigations reveal that increased synthesis and release of B2M are present in several malignant diseases.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"