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Product Name
Mouse CD79B/Ig-beta (His Tag) recombinant protein
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Description
Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.
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Protein name
B-cell antigen receptor complex-associated protein beta chain
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Protein short names
IG-BETA; IGB; CD79B; RP23-418O11.7; B29; IGBETA; AGM6
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Uniprot ID
P15530
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Gene Name
Cd79b; Igb
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse CD79B (P15530) extracellular domain (Met 1-Asp 158) was expressed, with a C-terminal polyhistidine tag.
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Protein Species
Mouse
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Molecular weight
The secreted recombinant mouse CD79B comprises 144 amino acids and has a calculated molecular mass of 16.4 kDa. As a result of glycosylation, the apparent molecular mass of the recombinant protein is approximately 25-35 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Mouse CD79B / B29 Protein (His Tag) SDS-PAGE
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