AZGP1 antibody

Cat.#: 107074

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Product Information

  • Product Name
    AZGP1 antibody
  • Documents
  • Description
    AZGP1 Mouse Monoclonal antibody. Positive IHC detected in human breast cancer tissue, human prostate cancer tissue, human prostate hyperplasia tissue. Positive WB detected in human plasma tissue. Observed molecular weight by Western-blot: 41 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    AZGP1 antibody; ZA2G antibody; ZAG antibody; Zinc alpha 2 glycoprotein antibody; Zn alpha 2 glycoprotein antibody; Zn alpha 2 GP antibody; ZNGP1 antibody
  • Isotype
    Mouse IgG1
  • Preparation
    This antibody was obtained by immunization of AZGP1 recombinant protein (Accession Number: NM_001185). Purification method: Protein G purified.
  • Clonality
    Monoclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    human plasma tissue were subjected to SDS PAGE followed by western blot with Catalog No:107074(AZGP1 Antibody) at dilution of 1:1000

    human plasma tissue were subjected to SDS PAGE followed by western blot with Catalog No:107074(AZGP1 Antibody) at dilution of 1:1000

    Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using Catalog No:107074(AZGP1 Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using Catalog No:107074(AZGP1 Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using Catalog No:107074(AZGP1 Antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using Catalog No:107074(AZGP1 Antibody) at dilution of 1:50 (under 40x lens)

  • Background
    Zinc-alpha-2-glycoprotein (AZGP1) is a soluble protein normally found in body fluids, functions as a lipid mobilizing factor (PMID: 19188554). It is known to be expressed in the secretory epithelia of the liver, lung, breast, GI tract and sweat glands, sharing significant structural similarity with the class I major histocompatibility complex (MHC) antigens (PMID: 3422450). AZGP1 is involved in carcinogenesis and differentiation. Altered expression of AZGP1 has been reported in breast cancer, prostate cancer and lung adenocarcinoma, hepatocellular carcinoma, pancreatic carcinoma and oral tumors (PMID: 22625427).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"