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Product Name
ATP1A2-Specific antibody
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Description
ATP1A2-Specific Rabbit Polyclonal antibody. Positive IHC detected in human skeletal muscle tissue, mouse heart tissue. Positive WB detected in mouse brain tissue, human brain tissue. Observed molecular weight by Western-blot: 100 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
ATP1A2 antibody; FHM2 antibody; KIAA0778 antibody; MHP2 antibody; Sodium pump subunit alpha 2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_000702). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:108343(ATP1A2 antibody) at dilution of 1:800
Immunohistochemical of paraffin-embedded human skeletal muscle using Catalog No:108343(ATP1A2 antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human skeletal muscle using Catalog No:108343(ATP1A2 antibody) at dilution of 1:50 (under 40x lens)
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Background
ATP1A2, also named as KIAA0778, belongs to the cation transport ATPase (P-type) family and Type IIC subfamily. It is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. Defects in ATP1A2 are the cause of familial hemiplegic migraine type 2 (FHM2). Defects in ATP1A2 are a cause of alternating hemiplegia of childhood (AHC). This antibody is specific to ATP1A2.
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