ATG5 antibody

ATG5 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

ATG5 Mouse Monoclonal antibody. Positive WB detected in K-562 cells, HeLa cells. Observed molecular weight by Western-blot: 55 kDa

ELISA, WB

Human, Mouse; other species not tested.

APG5 antibody; APG5 LIKE antibody; APG5L antibody; Apoptosis specific protein antibody; ASP antibody; ATG5 antibody; Autophagy protein 5 antibody; hAPG5 antibody

Mouse IgM

This antibody was obtained by immunization of ATG5 recombinant protein (Accession Number: NM_004849). Purification method: Caprylic acid/ammonium sulfate precipitation.

Monoclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

ATG5, also named as APG5L and ASP, belongs to the ATG5 family. It is required for autophagy. It plays an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. It mediates autophagosome-independent host protection.