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Product Name
ATAD2 Polyclonal Antibody
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Description
Polyclonal antibody to ATAD2
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Tested applications
WB
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Species reactivity
Human
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Alternative names
ATAD2 antibody; ANCCA antibody; CT137 antibody; PRO2000 antibody; ATPase family, AAA domain containing 2 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human ATAD2
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, pH7.3.
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Storage instructions
Store at 4℃. Avoid freeze / thaw cycles.
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Applications
WB 1:200 - 1:1000
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Validations
Western blot - ATAD2 Polyclonal Antibody
Western blot analysis of extracts of HeLa cells, using ATAD2 antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
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Background
May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"