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Product Name
ASIC2 antibody
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Description
ASIC2 Rabbit Polyclonal antibody. Positive WB detected in rat brain tissue. Positive IP detected in mouse brain tissue. Observed molecular weight by Western-blot: 70 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
ACCN antibody; ACCN1 antibody; Acid sensing ion channel 2 antibody; ASIC2 antibody; ASIC2a antibody; BNaC1 antibody; BNC1 antibody; Brain sodium channel 1 antibody; hBNaC1 antibody; Mammalian degenerin homolog antibody; MDEG antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of ASIC2 recombinant protein (Accession Number: NM_001094). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
IP: 1:200-1:2000
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Validations
rat brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:108229(ACCN1 Antibody) at dilution of 1:300
IP Result of anti-ACCN1 (IP:Catalog No:108229, 4ug; Detection:Catalog No:108229 1:500) with mouse brain tissue lysate 4000ug.
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Background
ASIC2 (acid-sensing ion channel 2), also known as ACCN1 (amiloride-sensitive cation channel 1, neuronal), is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. ASIC2 is widely expressed in the central nervous system (CNS), may playing a role in neurotransmission. It has two alternatively spliced variants, ASIC2a and ASIC2b.
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References
- Xu J, Wang N, Luo JH, Xia J. Syntabulin regulates the trafficking of PICK1-containing vesicles in neurons. Scientific reports. 6:20924. 2016.
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