Human DOPA Decarboxylase/DDC (His Tag) recombinant protein

Cat.#: 500922

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Product Information

  • Product Name
    Human DOPA Decarboxylase/DDC (His Tag) recombinant protein
  • Documents
  • Description
    Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.
  • Protein name
    Aromatic-L-amino-acid decarboxylase
  • Protein short names
    DDC; RP23-373H2.3; AADC; DOPA DECARBOXYLASE
  • Uniprot ID
    Q53Y41
  • Gene Name
    DDC; AADC
  • Source/Expression Host
    Baculovirus-Insect Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the full length of human DDC (NP_000781.1) (Met 1-Glu 480) was expressed with a polyhistidine tag at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human DDC consists of 490 amino acids and predicts a molecular mass of 55 kDa. It migrates as an approximately 48 kDa protein in SDS-PAGE under reducing conditions.
  • Purity
    > 90 % as determined by SDS-PAGE
  • Activity
    Measured by its ability to convert the substrate 3, 4-dihydroxy L-phenylalanine (L-Dopa) to 3, 4-dihydroxyphenylethylamine (dopamine). The dopamine product is measured by its absorbance at 340 nm after derivatization with trinitrobenzene sulfonic acid The specific activity is >1500 pmoles/min/μg.
  • Validations

    Human DOPA Decarboxylase / DDC Protein (His Tag) SDS-PAGE

    Human DOPA Decarboxylase / DDC Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"