ARHGEF4 antibody

Cat.#: 108186

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Product Information

  • Product Name
    ARHGEF4 antibody
  • Documents
  • Description
    ARHGEF4 Rabbit Polyclonal antibody. Positive IHC detected in human brain tissue. Positive WB detected in mouse brain tissue. Positive IP detected in mouse brain tissue. Observed molecular weight by Western-blot: 72 kDa
  • Tested applications
    ELISA, IHC, WB, IP
  • Species reactivity
    Human, Mouse; other species not tested.
  • Alternative names
    ARHGEF4 antibody; ASEF antibody; ASEF1 antibody; GEF4 antibody; KIAA1112 antibody; STM6 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Peptide (Accession Number: NM_015320). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IP: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:108186(ARHGEF4 Antibody) at dilution of 1:1000

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:108186(ARHGEF4 Antibody) at dilution of 1:1000

    WB result of Catalog No:108186 (ARHGEF4 Antibody).

    WB result of Catalog No:108186 (ARHGEF4 Antibody).

    Immunohistochemistry of paraffin-embedded human brain tissue slide using Catalog No:108186(ARHGEF4 Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human brain tissue slide using Catalog No:108186(ARHGEF4 Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human brain tissue slide using Catalog No:108186(ARHGEF4 Antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemistry of paraffin-embedded human brain tissue slide using Catalog No:108186(ARHGEF4 Antibody) at dilution of 1:50 (under 40x lens)

    IP Result of anti-ARHGEF4 (IP:Catalog No:108186, 4ug; Detection:Catalog No:108186 1:1000) with mouse brain tissue lysate 4000ug.

    IP Result of anti-ARHGEF4 (IP:Catalog No:108186, 4ug; Detection:Catalog No:108186 1:1000) with mouse brain tissue lysate 4000ug.

  • Background
    ARHGEF4, also named as KIAA1112 and Asef, acts as guanine nucleotide exchange factor (GEF) for RhoA and RAC1 GTPases. Binding of APC, ARHGEF4 may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion.(PMID: 10873612). This antibody is specific to ARHGEF4.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"