ARHGEF11 Polyclonal Antibody

Cat.#: 165631

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Product Information

  • Product Name
    ARHGEF11 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to ARHGEF11
  • Tested applications
    WB, IHC
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    ARHGEF11 antibody; GTRAP48 antibody; PDZ-RHOGEF antibody; rho guanine nucleotide exchange factor 11 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human ARHGEF11
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
    IHC 1:50 - 1:100
  • Validations

    Western blot - ARHGEF11 Polyclonal Antibody

    Western blot - ARHGEF11 Polyclonal Antibody

    Western blot analysis of extracts of mouse brain, using ARHGEF11 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 90s.

    Immunohistochemistry - ARHGEF11 Polyclonal Antibody

    Immunohistochemistry - ARHGEF11 Polyclonal Antibody

    Immunohistochemistry of paraffin-embedded human prostate cancer using ARHGEF11 antibody (40x lens).

    Immunohistochemistry - ARHGEF11 Polyclonal Antibody

    Immunohistochemistry - ARHGEF11 Polyclonal Antibody

    Immunohistochemistry of paraffin-embedded human lung using ARHGEF11 antibody (40x lens).

    Immunohistochemistry - ARHGEF11 Polyclonal Antibody

    Immunohistochemistry - ARHGEF11 Polyclonal Antibody

    Immunohistochemistry of paraffin-embedded human colon using ARHGEF11 antibody (40x lens).

  • Background
    May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"