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Product Name
ARG2 antibody
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Description
ARG2 Rabbit Polyclonal antibody. Positive IHC detected in human prostate cancer tissue, human kidney tissue. Positive WB detected in HEK-293 cells, mouse liver tissue, rat liver tissue. Observed molecular weight by Western-blot: 39-42kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
ARG2 antibody; Arginase 2 antibody; mitOChondrial antibody; arginase antibody; type II antibody; Kidney type arginase antibody; Non hepatic arginase antibody; Type II arginase antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of ARG2 recombinant protein (Accession Number: NM_001172). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:108256(ARG2 antibody) at dilution of 1:1000
Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:108256(ARG2 antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:108256(ARG2 antibody) at dilution of 1:100 (under 40x lens)
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Background
ARG2(Arginase-2, mitochondrial) is also named as kidney-type arginase, non-hepatic arginase and belongs to the arginase family. It may play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis.
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References
- Tavori H, Fan D, Giunzioni I. Macrophage-derived apoESendai suppresses atherosclerosis while causing lipoprotein glomerulopathy in hyperlipidemic mice. Journal of lipid research. 55(10):2073-81. 2014.
- Zhou R, Kang X, Tang B. Ornithine is a key mediator in hyperphosphatemia-mediated human umbilical vein endothelial cell apoptosis: Insights gained from metabolomics. Life sciences. 146:73-80. 2016.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"