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ARG2 antibody

Cat.#: 108256

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Product Information

  • Product Name
    ARG2 antibody
  • Documents
  • Description
    ARG2 Rabbit Polyclonal antibody. Positive IHC detected in human prostate cancer tissue, human kidney tissue. Positive WB detected in HEK-293 cells, mouse liver tissue, rat liver tissue. Observed molecular weight by Western-blot: 39-42kd
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    ARG2 antibody; Arginase 2 antibody; mitOChondrial antibody; arginase antibody; type II antibody; Kidney type arginase antibody; Non hepatic arginase antibody; Type II arginase antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of ARG2 recombinant protein (Accession Number: NM_001172). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:108256(ARG2 antibody) at dilution of 1:1000

    HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:108256(ARG2 antibody) at dilution of 1:1000

    Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:108256(ARG2 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:108256(ARG2 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:108256(ARG2 antibody) at dilution of 1:100 (under 40x lens)

    Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:108256(ARG2 antibody) at dilution of 1:100 (under 40x lens)

  • Background
    ARG2(Arginase-2, mitochondrial) is also named as kidney-type arginase, non-hepatic arginase and belongs to the arginase family. It may play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis.
  • References
    • Tavori H, Fan D, Giunzioni I. Macrophage-derived apoESendai suppresses atherosclerosis while causing lipoprotein glomerulopathy in hyperlipidemic mice. Journal of lipid research. 55(10):2073-81. 2014.
    • Zhou R, Kang X, Tang B. Ornithine is a key mediator in hyperphosphatemia-mediated human umbilical vein endothelial cell apoptosis: Insights gained from metabolomics. Life sciences. 146:73-80. 2016.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"