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Product Name
APOC1 Polyclonal Antibody
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Description
Polyclonal antibody to APOC1
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Tested applications
IHC
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Species reactivity
Human, Rat
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Alternative names
APOC1 antibody; Apo-CI antibody; ApoC-I antibody; apo-CIB antibody; apoC-IB antibody; apolipoprotein C1 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-83 of human APOC1 (NP_001636.1).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
IHC 1:50 - 1:100
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Validations
Immunohistochemistry - APOC1 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded rat liver using APOC1 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - APOC1 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human colon carcinoma using APOC1 antibody at dilution of 1:100 (40x lens).
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Background
Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"