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APAF1 Polyclonal Antibody

Cat.#: 160148

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Special Price 174.2 USD

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Product Information

  • Product Name
    APAF1 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to APAF1
  • Tested applications
    WB
  • Species reactivity
    Human
  • Alternative names
    APAF1 antibody; APAF-1 antibody; CED4 antibody; apoptotic protease-activating factor 1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human APAF1 (NP_863651.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
  • Validations

    Western blot - APAF1 Polyclonal Antibody

    Western blot - APAF1 Polyclonal Antibody

    Western blot analysis of extracts of 293 cells, using APAF1 antibody .

  • Background
    Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"