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Product Name
AP3D1 antibody
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Description
AP3D1 Rabbit Polyclonal antibody. Positive WB detected in NIH/3T3 cells, HeLa cells. Observed molecular weight by Western-blot: 110 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
ADTD antibody; AP 3 complex subunit delta antibody; AP 3 complex subunit delta 1 antibody; AP3D1 antibody; Delta adaptin antibody; hBLVR antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of AP3D1 recombinant protein (Accession Number: BC010065). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
NIH/3T3 cells were subjected to SDS PAGE followed by western blot with Catalog No:108123(AP3D1 antibody) at dilution of 1:300
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Background
Adaptor protein (AP) complexes are cytosolic heterotetramers that mediate the sorting of membrane proteins in the secretory and endocytic pathways. AP3D1 is a subunit of the AP-3 complex which is composed of two large adaptins (AP3D1 and AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). AP-3 complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.
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