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Product Name
AP1M2 antibody
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Description
AP1M2 Rabbit Polyclonal antibody. Positive IHC detected in human pancreas cancer tissue, human kidney tissue. Positive WB detected in mouse colon tissue, BxPC-3 cells, Hacat cells. Observed molecular weight by Western-blot: 50-55 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
AP 1 complex subunit mu 2 antibody; AP mu chain family member mu1B antibody; AP1 mu2 antibody; AP1M2 antibody; HSMU1B antibody; MU 1B antibody; Mu adaptin 2 antibody; MU1B antibody; Mu1B adaptin antibody; mu2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of AP1M2 recombinant protein (Accession Number: NM_001300887). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:10-1:100
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Validations
WB result of AP1M2 antibody (Catalog No:108118;1:500) with siRNA cell lysate.
mouse colon tissue were subjected to SDS PAGE followed by western blot with Catalog No:108118(AP1M2 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human pancreas cancer using Catalog No:108118(AP1M2 antibody) at dilution of 1:10 (under 10x lens)
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Background
AP1M2 is a subunit of the adaptor complex AP-1. It belongs to the adaptor complexes medium subunit family. Adaptor protein (AP) complexes are cytosolic heterotetramers that mediate the sorting of membrane proteins in the secretory and endocytic pathways. AP-1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors.
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