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Product Name
Anti-XRN2 antibody
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Description
Mouse monoclonal antibody to XRN2
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Tested applications
WB, IHC-P
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Species reactivity
Human
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Isotype
Mouse IgG1
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Preparation
This antigen of this antibody was recombinant protein
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Clonality
Monoclonal
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Formulation
Liquid, 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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Storage instructions
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
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Applications
WB: 1:500-1:2,000
IHC-P: 1:200-1:500
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Validations
Fig1: Western blot analysis of XRN2 on human XRN2 recombinant protein using anti-XRN2 antibody at 1/1,000 dilution.
Fig2: Western blot analysis of XRN2 on HEK293 (1) and XRN2-hIgGFc transfected HEK293 (2) cell lysate using anti-XRN2 antibody at 1/1,000 dilution.
Fig3: Western blot analysis of XRN2 on different cell lysate using anti-XRN2 antibody at 1/1,000 dilution.; Positive control:; Lane 1: Raw264.7; Lane 2: HEK293; Lane 3: NTERA-2; Lane 4: LNcap; Lane 5: HepG2; Lane 6: HEK293; Lane 7: Hela
Fig4: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-XRN2 antibody. Counter stained with hematoxylin.
Fig5: Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissue using anti- XRN2 antibody. Counter stained with hematoxylin.
- Background
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References
- Haas G et al. Identification of factors involved in target RNA-directed microRNA degradation. Nucleic Acids Res 44:2873-87 (2016).
- Gaulke CA et al. Intestinal Epithelial Barrier Disruption through Altered Mucosal MicroRNA Expression in Human Immunodeficiency Virus and Simian Immunodeficiency Virus Infections. J Virol 88:6268-80 (2014).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"