Anti-VDAC1 Rabbit antibody

Cat.#: 166680

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Product Information

  • Product Name
    Anti-VDAC1 Rabbit antibody
  • Documents
  • Description
    VDAC1 Rabbit polyclonal antibody
  • Tested applications
    WB, IHC-P
  • Species reactivity
    Human, Mouse, Rat
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthesized peptide derived from human VDAC1
  • Clonality
    Polyclonal
  • Formulation
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/500-1/2000

    IHC: 1/50-1/200

  • Validations

    Western blot analysis of VDAC1 expression in C2C12,THP-1,3T3,Jurakt and Hela cell lysates using VDAC1 antibody at 1/1000 dilution.Predicted band size:31KDa.Observed band size:31KDa.

    Western blot analysis of VDAC1 expression in C2C12,THP-1,3T3,Jurakt and Hela cell lysates using VDAC1 antibody at 1/1000 dilution.Predicted band size:31KDa.Observed band size:31KDa.

    Immunohistochemical analysis of paraffin-embedded human liver, using VDAC1 Antibody.

    Immunohistochemical analysis of paraffin-embedded human liver, using VDAC1 Antibody.

    Western blot analysis of Calreticulin expression in (1) HepG2 cell lysate; (2) Jurkat cell lysate.

    Western blot analysis of Calreticulin expression in (1) HepG2 cell lysate; (2) Jurkat cell lysate.

  • Background
    Swiss-Prot Acc.P21796.Voltage-dependent anion channel (VDAC), ubiquitously expressed and located in the outer mitochondrial membrane, is generally thought to be the primary means by which metabolites diffuse in and out of the mitochondria. In addition, this channel plays a role in apoptotic signaling. The change in mitochondrial permeability characteristic of apoptosis is mediated by Bcl-2 family proteins, which bind to VDAC, altering the channel kinetics.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"