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  • Anti-VASP Rabbit antibody

Anti-VASP Rabbit antibody

Cat.#: 168907

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Product Information

  • Product Name
    Anti-VASP Rabbit antibody
  • Documents
  • Description
    VASP Rabbit monoclonal antibody
  • Tested applications
    WB, IP
  • Species reactivity
    Human
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human VASP
  • Clonality
    Monoclonal antibody
  • Formulation
    50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000

    IP: 1/20

  • Validations

    Western blot detection of VASP in Hela cell lysates using VASP Rabbit mAb(1:500 diluted).Predicted band size:40kDa.Observed band size:40kDa.

    Western blot detection of VASP in Hela cell lysates using VASP Rabbit mAb(1:500 diluted).Predicted band size:40kDa.Observed band size:40kDa.

  • Background
    Swiss-Prot Acc.P50552.Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"