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Product Name
Anti-TRAF6BP/TAX1BP1 Rabbit antibody
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Description
TRAF6BP/TAX1BP1 Rabbit polyclonal antibody
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Tested applications
WB, IHC-P, ICC/IF
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Species reactivity
Human, Mouse, Rat
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Alternative names
T6BP; TXBP151; CALCOCO3 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human TRAF6BP
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/1000
IHC: 1/20
ICC/IF: 1/20
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Validations
Western blot detection of TRAF6BP/TAX1BP1 in K562,Hela cell lysates using TRAF6BP/TAX1BP1 Rabbit pAb(1:1000 diluted).Predicted band size:91kDa.Observed band size:91kDa.
Immunohistochemistry of TRAF6BP in paraffin-embedded Human lung cancer tissue using TRAF6BP Rabbit pAb at dilution 1/20
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Background
Swiss-Prot Acc.Q86VP1.Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"