Anti-TNFSF4 antibody

Anti-TNFSF4 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit Polyclonal to Human TNFSF4

IHC-P

Human OX-40L / TNFSF4 / CD252

tumor necrosis factor (ligand) superfamily antibody; member 4 antibody; TNFSF4 antibody; CD134L antibody; CD252 antibody; GP34 antibody; OX-40L antibody; OX4OL antibody; TXGP1 antibody; CD134 ligand antibody; OX40 antigen ligand antibody; OX40L antibody; TAX transcriptionally-activated glycoprotein 1 antibody; glycoprotein Gp34 antibody; tax-transcriptionally activated glycoprotein 1 (34kD) antibody; tumor necrosis factor ligand superfamily member 4 antibody; Txgp1 antibody; TXGP1L antibody; GP34 antibody; CD252 antibody; OX4OL antibody; TXGP1 antibody; CD134L antibody; OX-40L antibody; Ath1 antibody; gp34 antibody; Ath-1 antibody; Ox40l antibody; CD134L antibody; OX-40L antibody

Rabbit IgG

Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human OX-40L / TNFSF4 / CD252, and purified by antigen affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-mediated immunity. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. OX-40L is a ligand for receptor TNFRSF4/OX4. It is found to play a role in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.

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